月度归档： 2020 年 11 月

Aging in humans reversed with hyperbaric oxygen therapy

Aging, which happens over time in humans, has been biologically reversed by hyperbaric oxygen therapy, according to new research published in the journal Aging.

Scientists, led by Yafit Hachmo, from the Research and Development Unit, Shamir Medical Center, Tzrifin, Israel, turned back the human clock for 35 adults aged 64 and older by reversing two key areas of the body thought responsible for the frailty and ill-health that comes with growing older. Protective caps at the ends of chromosomes, known as telomeres, shorten, causing DNA to become damaged and cells to stop replicating as people age. At the same time, senescent cells build up in the body, preventing regeneration.

Increasing telomere length and getting rid of senescent cells is the focus of anti-aging research, with drugs being developed to target those areas, The Telegraph reported.

The 35 patients were repeatedly given pure oxygen in a hyperbaric chamber, which increased the length of their telomeres by 20%, a feat that has never been achieved before.

Scientists said the growth may mean that the telomeres of trial participants were now as long as they had been 25 years earlier.

The therapy also reduced senescent cells by up to 37%, enabling new healthy cells to regrow. Animal studies have shown that removing senescent cells extends the remaining life by more than 33%.

“Since telomere shortening is considered the ‘Holy Grail’ of the biology of aging, many pharmacological and environmental interventions are being extensively explored in the hopes of enabling telomere elongation,” said one of the scientists involved in the research, Professor Shai Efrati, director of the Sagol Center at Shamir Medical Center.

“The significant improvement of telomere length shown during and after these unique protocols provides the scientific community with a new foundation of understanding that aging can indeed be targeted and reversed at the basic cellular-biological level.”

Scientists believe aging itself is responsible for diseases such as Alzheimer’s, Parkinson’s, arthritis, cancer, heart disease, and diabetes.

It is known that obesity, smoking, lack of physical activity, vitamin deficiency, and inflammation can speed up the shortening of telomeres, demonstrating that they have a major impact on the length of life.

The 35 participants did not undergo any lifestyle, diet, or medication adjustments. Each patient was placed in a hyperbaric chamber for 90 minutes for five days a week over three months while breathing 100% oxygen through a mask.

The pressurized chamber allows more oxygen to be dissolved into the tissues and mimics a state of hypoxia, or oxygen shortage, which is known to have regenerating effects.

Previous trials have shown that eating a healthy diet can preserve telomere length, while high-intensity training for six months has been proven to lengthen telomeres by up to 5%.

The Israeli team has also previously demonstrated that pressurised oxygen therapy can improve cognitive decline.

“Until now, interventions such as lifestyle modifications and intense exercise were shown to have some inhibition effect on the expected telomere length shortening,” said Dr. Amir Hadanny, Chief Medical Research Officer of the Sagol Center for Hyperbaric Medicine and Research.

“However, what is remarkable to note in our study is that, in just three months of therapy, we were able to achieve such significant telomere elongation – at rates far beyond any of the currently available interventions or lifestyle modifications.

“With this pioneering study, we have opened a door for further research on the prolonged cellular impact of the therapy to reverse the aging process. After dedicating our research to exploring its impact on the areas of brain functionality and age-related cognitive decline, we have now uncovered, for the first time in humans, biological effects at the cellular level in healthy aging adults.”

The researchers pointed out that the study has several limitations and strengths to consider. First, the limited sample size has to be taken into account. Second, the lack of a control group.

“However, the study suggests impressive results on telomeres and senescent cell clearance, which weren’t observed in other interventions,” said the research paper.

2020 Best Portable Oxygen Concentrator Guide (Easy rules to operate oxygen concentrator for beginners)

What is Portable Oxygen Concentrator?

Portable oxygen concentrator is a device that has a built-in battery and can work autonomously during transportation. Depending on the size and power of the device, the battery life can vary from 1 to 8 hours.

Flow type for portable oxygen concentrators

Most mobile oxygen generation devices deliver oxygen in batches (pulsating flow. It is in order to conserve power. But some manufacturers allow for a constant supply of oxygen, regardless of the patient's inhalation.

If you have not decided which portable oxygen concentrator to buy – contact us for an experienced specialist consultation. Many models have additional accessories and external batteries. Moreover, they can save you money and extend your portable work time.

Portable oxygen concentrator is compact, easy to carry and have rechargeable batteries. Such concentrators are capable of autonomously providing a person with oxygen for several hours.

The peculiarity of most portable concentrators is that oxygen does not come in a continuous stream, but in portions, during each breath.

Where to buy Portable oxygen concentrator in china?

The benefits of oxygen therapy are famous worldwide. In addition, now these devices are available for domestic use also. Earlier, big clinics used to provide oxygen services. But now, you can easily buy it.

In order to carry out it at home, you need an oxygen concentrator. You can purchase this device from our store. We offer a large number of options from different price categories. We will tell you why this device is needed.

 

How the oxygen concentrator works?

Oxygen is the source of life for all organisms, and humans are no exception. With its participation, many important processes go in the circulatory system. If there is not enough oxygen, then hypoxia develops. Therefore, it leads to the following consequences:

• weakening of immunity;
• decreased vitality;
• violation of mental activity;
• headaches;
• muscle discomfort;
• disorders of the nervous system.

Most of the people do not have access to walks in the fresh air. Especially since in many areas it is hard to breathe due to the congestion of traffic, emissions from industries and boiler houses. Subsequently, pure oxygen therapy can correct the situation.

We can use oxygen therapy with a portable oxygen concentrator not only for adults, but also for children of any age. Similarly, we can fulfill the lack of oxygen either by breathing (through a cannula or mask) or by taking an oxygen cocktail.

 

The principle of operation of the oxygen concentrator is simple:

1. the device takes air from the atmosphere
2. The air passes through a "molecular sieve. Moreover, it retains nitrogen
3. as a result of cleaning, a gas mixture forms up in which 95% oxygen
4. Oxygen is supplied to the patient.

Portable Oxygen concentrators for the treatment of diseases

The main application of oxygen therapy is the treatment of diseases of the respiratory system:

• failure of the heart or respiratory system;
• cystic fibrosis;
• bronchial diseases, including asthma;
• chronic lung obstruction;
• Pulmonary hypertension.

The duration of a therapy session using a concentrator depends on the characteristics of the course of the disease. If you are taking oxygen for treatment, then you need to breathe for 0.5-1 hours a day.

This improves the general well-being of patients. With other diseases, it is possible to achieve:

• reduce shortness of breath;
• restoration of the work of the heart, kidneys and liver;
• Reducing the intoxication of the body.

Portable Oxygen concentrators are also common during the recovery period after surgery and after severe diseases. Oxygen therapy helps to quickly return to normal life and strengthen the immune system. In addition, more than 90% of patients report that they feel better after the sessions.

Home-use concentrators are a safe alternative to oxygen cylinders previously used for obstructive pulmonary disease. Now you can find them everywhere and everyone is using it as supportive therapy. The reason is, it brings a number of surprising benefits.

How does medical facility use Portable oxygen concentrator?

For COPD, longer sessions are supportive. Furthermore, they are key in treating obstruction of the lungs. Regular use of portable oxygen concentrator allows reducing the time of hospital stay, the number of relapses. Similarly, it also increases the patient's life expectancy by 5-6 years. When the lungs are weak, oxygen concentrators can help make patients more physically active.

Application for healthy people

Short-term oxygen therapy (on small flows) will be useful to everyone who lives in a metropolis or feels signs of hypoxia.

Generally, there are several categories of people who need to undergo oxygen therapy:

• smokers;
• women during the period of bearing a child;
• obese;
• Moreover, athletes and everyone who follows their figure;
• To old people.

Before purchasing a concentrator, go through an examination and get advice from your GP. It is important to strictly follow the regimen prescribed by your doctor. Be sure to specify in what dosage and form to take oxygen. If you are going to do inhalation, then it is necessary to conduct sessions with a certain duration.

 You should refrain from using the Portable oxygen concentrator when:

• exacerbation of chronic diseases
• gallstone disease
• allergies

If you plan to prepare drinks using portable oxygen concentrator, then you need to use for them only the basis for which you do not have an individual intolerance.

Oxygen therapy for children

In some cases, oxygen therapy is good in childhood. For correct and timely child development, a greater supply of oxygen is necessary. With its deficiency, the following are common observations:

• frequent respiratory diseases
• decreased academic performance
• problems with memorization and development
• Weakening of the immune system.

Most often, concentrator therapy is good for schoolchildren. It goes through in the form of oxygen cocktail courses. Healthy drinks are available on the basis of juices or herbal decoctions. Hence, it increases their benefits. Moreover, it is also important that the child does not have to be persuaded to try the cocktail.

Operating rules for Portable oxygen concentrator

Before using the device for the first time, you need to read the instructions for it. Her standard recommendations are:

 

1. Remember that oxygen is an explosive gas. Therefore, you need to use the concentrator where there are no sources with an open fire (gas stove, candle, and smoking person) and heating devices. You cannot leave the turned off device next to them either.
2. During the session, place the device at a distance of 30 centimeters from walls and furniture. This will allow the recycled air components to dissipate unhindered.
3. During long-term therapy, it is necessary to inhale the enriched mixture with a humidifier. Almost all portable oxygen concentratorshave it in the basic kit.
4. Nasal cannulas are used individually. Several people can use one breathing set (if included).
5. Maintenance of the concentrator is simple: you need to regularly change the water in the humidifier and clean / replace filters.

Conclusion

The number of inhalations depends on the instructions of your GP. It is not recommended to exceed the recommended dosage. He will select the appropriate inhalation mode and amount of oxygen for you.

If you are conducting therapy with Portable oxygen concentrator, then it should be a course. The duration of treatment should be from 4 to 5 weeks, and 1-2 servings of the cocktail should be taken per day.

How Portable hyperbaric chambers are helpful for acute mountain sickness (AMS)?

Why HBOT is important for mountaineers? 

Portable hyperbaric chambers have specially designed for the emergency uses. Basically, they are lightweight and very easy to handle. Moreover, you can carry them with you to use in some emergency cases in severe conditions. They are really helpful for mountaineers.

People who have to live on high mountains may face some critical problems to inhale. Portable chambers have actually designed for them.

Do you have any knowledge about HBOT or Hyperbaric Chamber Therapy? We are here for you to describe about HBOT and its uses. Furthermore, this guide has especially for those who want to know; How Portable hyperbaric chambers are helpful for AMS?

What is hyperbaric chamber therapy?

HBOT stands for Hyperbaric Chamber Therapy. In fact, Hyperbaric Chamber Therapy is a very special kind of oxygen treatment. This therapy has mostly used by some expert physicians in order to speed up carbon monoxide poisoning. Furthermore, by using Hyperbaric Chamber Therapy, they can also treat diseases like,

• stubborn wounds
• gangrene
• serious kinds of infections where oxygen has severely needed.

This special therapy first used in earlier of 20th century in US. And Orville Cunningham was the first physician who used of this therapy to save his patient. This patient got seriously affected by flu. Later he smashed it because he found not any beneficial uses of this chamber for other diseases.

But after some years in 1940s, the therapy again used by U.S. Navy. They used it to treat their deep-sea divers because they suffered in decompression sickness. And since now, HBOT has become one of the most popular therapy to use for mountaineers.

Because mountaineers often have to suffer from acute mountain sickness. For their need Portable hyperbaric chambers have introduced. 

How many kinds of hyperbaric chambers are?

There are two basic types of Modern Hyperbaric Chambers. These are,

1. Monoplace Hyperbaric Chamber
2. Multiplace Hyperbaric Chamber.

But nowadays the manufacturers of these chambers have also introduced portable chambers to use in some emergency conditions. Moreover, these are also beneficial in remote areas.

What are Portable hyperbaric chambers?

Portable chambers have designed for the purpose of some very emergency conditions and treatments. This is basically a best choice for those patients who often have to travel. Moreover, these portable chambers are extremely light in weight.

 

You can also expand it for at least two people. And you can use it with the help of an air compressor.

The patients, who have decompression sickness because of the scuba diving accidents, need to treat immediately. But it is not possible that all the time the hyperbaric chamber center is at nearer places. In such circumstances, Portable Hyperbaric Chambers are ideal to use.

Actually, they have designed to treat the patients in remote areas.

What are the design considerations for Portable hyperbaric chambers?

Mostly doctors call the portable chambers by another name like, soft chamber. Manufacturers have actually designed this chamber with the help of canvas or non-toxic urethane.

Moreover, it has specially attached with a special instrument of zipper to pack tightly after use or for transportation uses. You can easily install it anywhere, anytime and at anyplace whenever you want.

A patient in a portable chamber can easily supervise his own HBOT therapy without taking any help from an outsider. This is the most advantageous aspect of this chamber. For this perfect feature portable chamber is the most favorite HBOT chamber.

In fact, this is the best HBOT chamber for athletes and mountaineers.

Which diseases have cured in Portable hyperbaric chambers?

Like monoplace and multiplace hyperbaric chambers, Portable hyperbaric chambers play the same role to treat the patients. In portable chambers, you can also treat the same diseases in the same way. Because the HBOT therapy gives the same results in these portable chambers.

 

The Hyperbaric Chamber Therapy has now become the most common treatment to speed up the healing process of your body. This is a perfect treatment for improving your blood circulation.

Furthermore, it extremely helps your body to fight against several risky infections. Most of the physicians use HBOT therapy in order to treat and cure for several neurological disruptions and disorders.

Nowadays it has become the physicians first choice to treat the patients having carbon monoxide poisoning. Furthermore, it is also a perfect treatment for,

• scuba divers
• miners
• firefighters, etc.

HBOT has now greatly preferred by the physicians to treat several severe conditions relating to burns and bone diseases, like:

1. Cyanide poisoning
2. Gas gangrene
3. Carbon monoxide poisoning
4. Decompression sickness
5. Gas or air bubble trapped in a blood vessel
6. A severe infection in a bone
7. Diabetic wounds which don't heal rapidly
8. Crush injuries and many more.

Portable hyperbaric chambers are greatly beneficial for all the above diseases just like the other two main types of chambers.

What is altitude mountain sickness (AMS)?

AMS stands for Altitude Mountain Sickness or Acute Mountain Sickness. Mostly people have a negative health effect when they go to high mountains. Moreover, it also happens with those people who live on high mountains.

There is less amount of oxygen on the high altitudes and so mountaineers have to suffer from it. All of them often affected by acute mountain sickness (AMS). Basically, it is the negative health impact which mostly effects the people at extreme altitudes.

You suffer when you suddenly go from high pressure of oxygen to low amounts at the top of the mountains. However, its painful symptoms are:

• Dizziness
• Vomiting
• Great trouble occurs in inhaling during sleep
• Tiredness and exhaustion
• Headache, etc.

How Portable hyperbaric chambers can treat acute mountain sickness (AMS)?

As we have already described you that Altitude Mountain Sickness or AMS occurs when you travel to high mountains. You have to suffer in highly painful sickness. Furthermore, your breathing becomes more painful and you can indulge in some serious and dangerous diseases.

So, in Portable hyperbaric chambers you can instantly cure yourself in order to secure yourself from such painful symptoms. You can easily hold portable chamber with you and treat yourself more easily. As the famous quote is, “prevention is better than the cure”.

Basically, it will be right to say that hyperbaric chamber therapy is an ideal solution for AMS patients.

However, mountaineers and military officers can carry the portable chambers along with them without any hassle.

Some important precaution during the treatment of AMS in Portable hyperbaric chambers

Although portable chambers are extremely beneficial to treat diseases like, acute mountain sickness (AMS) and many more. But you should treat in this chamber by following some important precautions.

Moreover, these important precautions to use Portable hyperbaric chambers for HBOT therapy are:

• You should only use hyperbaric chamber therapy after prescribed by an expert physician.
• Patients with low or mild AMS disease should not use the therapy.
• Pressurized bags in HBOT chambers have not designed to cure the gentle symptoms of AMS.
• After some mild symptoms you must take some better rest before ascending.
• The AMS patient should not treat himself alone.
• Portable chambers are ideal only in some severe and emergency situations.
• It is just a treatment not a magic, so always follow some beneficial instructions before travelling on high altitudes.
• Always use Portable hyperbaric chambersunder an expert or well-trained person to avoid any trouble.

Conclusion:

Portable chambers are greatly advantageous as you can use it anywhere. Moreover, you can take advantages from it at home or any other place which you prefer. As HBOT therapy has now become the first choice of the doctors for rapid healing of some mild wounds.

Additionally, this therapy is really effective for several diseases which we have mentioned above. All types of hyperbaric chambers are beneficial according to the situations and some different circumstances. All are important to treat patients but Portable hyperbaric chambers are more convenient in comparison to the remaining two.